Columbo’s nephew Andy Parma marries model Melissa Hays, and after their lavish wedding reception, Melissa disappears mysteriously. 

When Andy, a police officer, call his famous uncle for help, it seems that no murder has been committed — and maybe this time, Lt. Columbo will be able to prevent one. In his usual astute manner, Columbo begins to search the hotel room for clues and witnesses, hoping to save his nephew’s bride before it’s too late.